Gene expression reveals that different types of human cell can work as a unit. These cellular modules, found in several tissues, change during disease. However, suitable computational methods are ...

Numerous genetic studies have identified many risk variants for type 2 diabetes (T2D)—but which genes and proteins are ...

Genetic studies have revealed many genes linked to both common and rare disease, but to understand how those genes bring about disease and use those insights to help develop therapies, scientists need ...

Spatial biology is a series of techniques with which scientists collect detailed cellular information and examine the positional context of cells in a tissue. Individual cells differentially use their ...

An international team of researchers reached a major milestone in decoding the human genome by linking genes across all chromosome of many individual people to specific tissues and disease processes.

Nucleic acid extraction from biological samples is inherently difficult to execute consistently across different tissue types. Some tissue matrices are fibrous, contained in protective cell walls, or ...

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations. For biologists, ...

The average adult male has around 36 trillion cells in their body, while average adult females have 28 trillion, researchers have found. Unexpectedly, the mass of small cells in our bodies, such as ...

In a recent study published in Immunology, researchers investigated populations of regulatory T cells (Treg), a type of white blood cell, in various tissues. Study: The tissue-resident regulatory T ...

For each type of tissue, the team made clusters of varying sizes. They reasoned that if the tissue's response is ruled by the flow between cells, then the bigger a tissue, the longer it should take ...