A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction ...

Researchers are testing a new approach to repair early memory loss by protecting brain connections affected in Alzheimer’s ...

Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...

Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...

Researchers have found that a natural aging-related molecule can repair key memory processes affected by Alzheimer’s disease.

A longevity-linked metabolite restored key memory processes in Alzheimer’s models, highlighting aging biology as a promising therapeutic target. Singapore ranks among the countries with the longest ...

As animals experience new things, the connections between neurons, called synapses, strengthen or weaken in response to events and the activity they cause in the brain. Neuroscientists believe that ...

Researchers at the universities of Freiburg in Germany and Geneva in Switzerland show that even a nap is enough to reorganise ...

This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...

Li’s study, “TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain," was recently published in The Journal of Clinical ...