One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs). These small molecule drugs form covalent bonds with their ...
AN attempt 1 to resolve misunderstandings regarding ionic-covalent bonding in solids has been criticized in a recent article by Mooser and Pearson 2. It should be pointed out, however, that their ...
The latest short science news items from C&EN. Open an introductory chemistry textbook. What is a covalent bond? A covalent bond occurs when atoms share electrons in a molecule. What is a hydrogen ...
Prior to 2000, many drugs that formed a covalent bond with targets did so non-selectively, which often led to undesired side effects when compared to non-covalent drugs. This led to the belief that ...
The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
A group of researchers at the University of Tokyo have spent years testing the limits of chemical bonds. And now, after years of work, they've finally explored an idea originally proposed in 1931: a ...
Chemistry students the world over are familiar with covalent bonds and hydrogen bonds. Now a study has revealed a strange variety of bond that acts like a hybrid of the two. Its properties raise ...
In the battle against B-cell cancers, drugs that target the enzyme Bruton tyrosine kinase (BTK) have transformed treatment. Before the first BTK inhibitor, ibrutinib, came on the market in 2013, ...
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