New research revealed contrasting roles for the SNAP23 protein in pancreatic secretion of digestive enzymes and hormones such as insulin. Inhibiting SNAP23 with a potential new diabetes drug enabled ...

The type II secretion system (T2SS) is a double-membrane-spanning protein secretion system composed of 12–15 different general secretory pathway (Gsp) proteins that are present in various copy numbers ...

A multi-institutional group of researchers led by the Hubrecht Institute and Roche's Institute of Human Biology has developed strategies to identify regulators of intestinal hormone secretion. In ...

The secretion of fluids like saliva and digestive juices are important in countless activities that keep our bodies running day and night. When secretions are disrupted, diseases like dry mouth and ...

Research reveals opposing roles for SNAP23 protein in the enzyme- and hormone-secretion functions of the pancreas; SNAP23 inhibitor increased insulin secretion in mice, suggesting potential use as a ...