Ribosomal subunit assembly and biogenesis constitute a fundamental process vital for cellular protein synthesis across all domains of life. This complex, multi-step pathway involves the transcription ...

The ribosome is a fundamental cellular machine responsible for protein synthesis. Its complex structure, comprising distinct functional centres such as the peptidyl transferase centre (PTC) and the ...

Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses. A new study of 500,000 individuals indicates that people who have more copies ...

Using cryo-electron microscopy, researchers show the factors that affect frameshifting during translation of the virus. Disrupting the frameshifting process in the virus could be a potential target ...

The enzyme that makes RNA from a DNA template is altered to slow the production of ribosomal RNA (rRNA), the most abundant type of RNA within cells, when resources are scarce and the bacteria ...

In a recent study posted to the bioRxiv* preprint server, the team of researchers explored the protein-protein interaction between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...

Ribosomes are the cell's protein factories, which read the genetic code and assemble the proteins that every organism needs to live. But as far as how ribosomes themselves were formed, tantalizingly ...

Proteins are the key players that regulate cellular structure and function. DNA, which functions as the blueprint for protein synthesis, is first transcribed into a messenger RNA (mRNA), which is ...

Researchers find that deficiency in RPL3L, a ribosome expressed in heart and skeletal muscle, impairs cardiac contractility due to delayed mRNA translation Fukuoka, Japan—A team of researchers have ...