Bottom Line: Potassium channels play an important role in controlling the electrical activity of neurons in the brain. We identified and characterized a new compound, called GiGA1, that selectively ...
Researchers find blocking the KCNB2 gene can slow tumor growth, paving the way for next-gen treatments for childhood brain cancer. Scientists at The Hospital for Sick Children (SickKids) have ...
A group from The Mount Sinai Hospital / Mount Sinai School of Medicine have identified and characterized a novel a GIRK1-selective activator, GiGA1 capable of selectively opening a subset of G-protein ...
Ion selectivity is an important property of cell membrane ion channels. For example, potassium ion channels are more permeable to potassium ions than to sodium ions. The mechanism underlying the ready ...
Do only potassium ions pass through the selectivity filter of a potassium channel, or are there water molecules between the ions? This question has been a source of controversy for years. Researchers ...
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