(A) Overview of the cohort, including all de novo acute megakaryoblastic leukemia subtypes (n = 75), compared with mononuclear cells derived from the bone marrow (BM) of non-cancer donors under 18 ...

Epigenome remodeling, including widespread changes to DNA methylation and 3D chromatin structure, is increasingly recognized as an important mechanism of gene deregulation in cancer. For example, at ...

Researchers from IIIT Hyderabad are using cutting-edge technologies for early detection of cancer, and more personalised ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...

If mothers smoke during pregnancy, they influence the epigenetic programming of their unborn child's genetic make-up in the long term. This may give rise to an increased risk of the development of ...

The central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product protein. This absolute theory has been debunked because ...

Salk Institute researchers find new mode of epigenetic targeting, showing for the first time that genetic sequences can direct new DNA methylation patterns in plants LA JOLLA (November 21, 2025)—All ...