The well-established notion that malignant tumors depend on angiogenesis to grow and metastasize (Carmeliet and Jain, 2000) has stimulated great interest on the potential clinical implications of the ...
A randomized phase II study of pazopanib in castrate-sensitive prostate cancer: A University of Chicago phase II consortium/DoD Prostate Cancer Clinical Trials Consortium study. Background: TRC105 is ...
Phase I first-in-human study of the centromere-associated protein E (CENP-E) inhibitor GSK923295 in patients with advanced solid tumors (study CPE107602). Background: CD105 (endoglin) is an angiogenic ...
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