Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Understanding the genetic mechanisms linking genome variations, such as single-nucleotide polymorphisms (SNPs), to phenotypes ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to ...

There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

Translocations are chromosomal “cut and paste” errors that drive many lymphomas, a type of blood cancer and the sixth most common form of cancer overall. This includes mantle cell lymphoma, a rare but ...

Researchers have developed a new computational approach that uncovers possible drugs for specific cellular targets for ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...