Generations of studying the root cause of schizophrenia have largely converged around a single theory: the “dopamine hypothesis,” which postulates that a combination of genetic susceptibility, ...

Autoreceptors provide an important inhibitory feedback mechanism for dopamine neurons by altering neuronal functions in response to changes in extracellular levels of dopamine. Elevated dopamine may ...

An extremely important therapeutic advantage of atypical antipsychotic drugs, such as clozapine and olanzapine, is improvement of cognitive function in schizophrenia. It is now acknowledged that trait ...