Chronic alcohol consumption profoundly alters gene expression in key brain regions involved in reward, impulse control, and ...

Post-mortem brain analysis shows decades of alcohol use significantly alter endocannabinoid gene expression in the prefrontal cortex and nucleus accumbens. Increased CB1, reduced CB2, altered GPR55 ...

New research suggests that the path to alcohol dependence may differ depending on when the condition begins. A study published in Drug and Alcohol Dependence identifies distinct roles for genetic ...

The brains of 18 patients with chronic Alcohol Use Disorder were studied post-mortem to look at the health impacts on the brain of excessive drinking.

New research shows chronic alcohol use rewires gene activity in human brain regions that control reward and decision-making, ...

"I have taken more out of alcohol than alcohol has taken from me,'' Winston Churchill once observed. And there's plenty of evidence that light to moderate alcohol consumption can have health benefits ...

People who carry a high genetic risk for alcohol use disorder may have brain immune cells that respond differently to alcohol exposure, according to new research published in Science Advances. Using ...

Members of the study (Left to right): Dr Tirtha Das Banerjee, Department of Biological Sciences, NUS; Dr. Joshua Raine, Research Fellow; Dr. Caroline Kibat, Senior Research Fellow; Study Lead ...

Background The ventral tegmental area (VTA) is a key brain region for dopamine production and the regulation of reward-related behaviors. While dopaminergic neurons have traditionally been considered ...